Comparison of the effectiveness of the antibiotics Fosfomycin and levofloxacin in acute cystitis: a systematic review and meta-analysis

Urinary tract infection or UTI is an caused by microorganisms that grow in the human urinary tract. Cystitis a (UTI) bladder (Li & Lesli, 2018). According to National Kidney and Urological Diseases Information Clearinghouse NKUDIC, infections are second most common infectious disease after respiratory infections, 8.3 million cases reported annually. can affect patients ranging from new-borns elderly. The main treatment for using antibiotics according 2015 Guidelines on Infections of European Association Urology (EAU). Fosfomycin therapy cystitis while levofloxacin alternative therapy. cystitis, but drug commonly found market levofloxacin. Purpose. This study aims compare effectiveness antibiotic with acute cystitis. method. meta-analysis research uses various literature sourced Cochrane, PubMed, Google Scholar, ScienceDirect. A search keywords “Fosfomycin” “levofloxacin” “cystitis” “acute”. Review Manager 5.4 application. Results. more effective against E. coli bacteria, S. saprophyticus bacteria. bacteria resistant than Fosfomycin, levofloxaci.